2. Signaling Pathways
  3. Anti-infection
  4. Parasite

Parasite

Parasite

Related Products

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Antiparasitics are a class of medications which are indicated for the treatment of parasitic diseases such as nematodes, cestodes, trematodes, and infectious protozoa.

Parasite Isoform Specific Products:

Parasite Isoform Comparison
Cat. No. Product Name Effect Purity Chemical Structure
  • HY-17506R
    Azithromycin (Standard)
    Azithromycin (Standard) is the analytical standard of Azithromycin. This product is intended for research and analytical applications. Azithromycin is a macrolide antibiotic useful for the treatment of a number of bacterial infections.
    Azithromycin (Standard)
  • HY-17596S
    Closantel-13C6
    		Inhibitor
    Closantel-13C6 is the 13C6 labeled Closantel. Closantel is a halogenated salicylanilide with a potent anti-parasitic activity. Closantel is a potent and highly specific Onchocerca volvulus chitinase (OvCHT1) inhibitor with an IC50 of 1.6 μM and a Ki of 468 nM. Closantel inhibits the O. volvulus L3 to L4 molt of developing.
    Closantel-<sup>13</sup>C<sub>6</sub>
  • HY-B0826R
    Spirodiclofen (Standard)
    		Inhibitor
    Spirodiclofen (Standard) is the analytical standard of Spirodiclofen. This product is intended for research and analytical applications.
    Spirodiclofen (Standard)
  • HY-108640
    HLI373
    		Inhibitor
    HLI373 is an efficacious Hdm2 inhibitor. HLI373 inhibits the ubiquitin ligase activity of Hdm2. HLI373 is effective in inducing apoptosis of several tumor cells that are sensitive to DNA-damaging agents. Antimalarial activity.
    HLI373
  • HY-149937
    Antimalarial agent 24
    		Inhibitor
    Antimalarial agent 24 (Compound 7) is an antimalarial agent in vitro. Antimalarial agent 24 inhibits P. falciparum W2 strain with an IC50 of 0.81 μM. Antimalarial agent 24 displays a CC50 higher than 200 μM against HepG2 cells.
    Antimalarial agent 24
  • HY-P4757
    N1-Glutathionyl-spermidine disulfide
    		Inhibitor
    N1-Glutathionyl-spermidine disulfide is a substrate of trypanothione reductase.
    N1-Glutathionyl-spermidine disulfide
  • HY-B1751A
    Quinidine sulfate
    		Inhibitor
    Quinidine Monosulfate is an antiarrhythmic agent. Quinidine Monosulfate is a potent, orally active, selective cytochrome P450db inhibitor. Quinidine Monosulfate is also a K+ channel blocker with an IC50 of 19.9 μM, and can induce apoptosis. Quinidine Monosulfate can be used for malaria research.
    Quinidine sulfate
  • HY-168962
    HDAC-IN-88
    		Inhibitor
    HDAC-IN-88 (Compound HJ-9) is the inhibitor for HDAC that inhibits HDAC6, HDAC1, HDAC2, HDAC8 and HDAC3 with IC50s of 0.226, 1.103, 2.308, 3.255 and 3.864 μM, respectively. HDAC-IN-88 inhibits the proliferation of cancer cell HepG2, HCT116 and MV4-11 with IC50 of 5.47, 9.78 and 0.38 μM, inhibits the migration of HCT116, arrests the cell cycle at G0/G1 phase, and induces apoptosis and autophagy in MV4-11. HDAC-IN-88 reduces ROS level and mitochondrial membrane potential. HDAC-IN-88 exhibits antimalarial activity that inhibits P. falciparum 3D7 with EC50 of 165 nM. HDAC-IN-88 also exhibits anti-angiogenic activity.
    HDAC-IN-88
  • HY-125159
    Derquantel
    		Inhibitor
    Derquantel is a potent anthelmintic. Derquantel causes flaccid paralysis and expulsion of nematodes.
    Derquantel
  • HY-149961
    Anti-inflammatory agent 40
    		Inhibitor
    Anti-inflammatory agent 40 is a potential and orally active anti-malarial and anti-inflammatory agent. Anti-inflammatory agent 40 inhibits carrageenan induced paw swelling in vivo.
    Anti-inflammatory agent 40
  • HY-12651AS
    Primaquine-13C,d3
    Primaquine-13C,d3 is the deuterium and 13C labeled Primaquine.
    Primaquine-<sup>13</sup>C,d<sub>3</sub>
  • HY-153547
    HSP90-IN-21
    		Inhibitor
    HSP90-IN-21 (5e) is an antiplasmodial agent, with IC50 values of 0.04, 0.17 and 2.91 μM against erythrocytic stage of P. falciparum (Pf3D7 and PfDd2 strains), cytotoxicity of human liver hepatocellular carcinoma cell line (HepG2), respectively.
    HSP90-IN-21
  • HY-148035
    Plm IV inhibitor-2
    		Inhibitor
    Plm IV inhibitor-2 (compound 3) is a potent digestive vacuole plasmepsins IV (Plm IV) inhibitor with IC50 values of 24 nM, 70 nM and 0.3 μM for Plm IV, II and I, respectively. Plm IV inhibitor-2 can be used to research malaria caused by Plasmodium parasites.
    Plm IV inhibitor-2
  • HY-161325
    Antileishmanial agent-26
    		Inhibitor
    Antileishmanial agent-26 (Compound 69) is a guanidine-containing compound with anti-Leishmania donovani activity. Its IC50 value against Leishmania donovani is 5.67 μM, and its CC50 value against THP-1 is 3.79 μM. Antileishmanial agent-26 can be used in the research of tropical diseases.
    Antileishmanial agent-26
  • HY-151195
    20S Proteasome-IN-4
    20S Proteasome-IN-4 (Compound 7) is a brain-penetrant, parasite-selective, orally active 20S proteasome inhibitor with an IC50 of 6.3 nM against T. b. brucei 20S proteasome. 20S Proteasome-IN-4 can be used for the research of human African trypanosomiasis (HAT).
    20S Proteasome-IN-4
  • HY-116433
    Nequinate
    		Inhibitor
    Nequinate, a quinoline compound, is an anticoccidial agent against cecal coccidiosis (Eimeria tenella) infections. Nequinate inhibits xanthine oxidoreductase (XOD) activity.
    Nequinate
  • HY-W779377
    Erythromycin B
    		Inhibitor
    Erythromycin B has anti-malarial activity and effectively inhibits the asexual reproduction of Plasmodium falciparum.
    Erythromycin B
  • HY-W399186
    Methylclonazepam
    		Control
    Methylclonazepam is a benzodiazepine with anxiolytic activity. Methylclonazepam inhibits the absorption of 5-hydroxytryptamine by Schistosoma mansoni. Methylclonazepam derivatives have anti-Schistosoma mansoni activity.
    Methylclonazepam
  • HY-N1453R
    Hypocrellin B (Standard)
    		Inhibitor
    Hypocrellin B (Standard) is the analytical standard of Hypocrellin B. This product is intended for research and analytical applications. Hypocrellin B, a pigment isolated from the fungi Hypocrella bambusae and Shiraia bambusicola, is an apoptosis inducer. Hypocrellin B can be used as a photosensitizer for photodynamic therapy of cancer. Hypocrellin B also has antimicrobial and antileishmanial activities[1][2][3].
    Hypocrellin B (Standard)
  • HY-126744
    Juncin E
    		Inhibitor
    Juncin E is a diterpenoid found in the soft coral Junceella juncea that exhibits significant insecticidal activity against the larvae of two important agricultural pests: southern corn rootworm and tobacco armyworm.
    Juncin E
Parasite Isoform Comparison

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